Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men

نویسندگان

  • Kanae Oda
  • Nobuyuki Miyatake
  • Noriko Sakano
  • Takeshi Saito
  • Motohiko Miyachi
  • Izumi Tabata
  • Takeyuki Numata
چکیده

OBJECTIVE To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. METHODS A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. RESULTS Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by Σ[metabolic equivalents × h per week (METs⋅h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. CONCLUSION Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ارتباط سطح سرمی IL-18 با گرلین آسیل‌دار، هورمون رشد، مقاومت انسولینی و پروفایل چربی در مردان چاق و لاغر

Introduction: Interleukin-18 (IL-18) is a strong proinflammatory cytokine that its increased levels are associated with obesity, metabolic syndrome, insulin resistance, dyslipidemia, and atherosclerosis. Thus, the purpose of this study was to investigate the relationships between serum interleukin-18 concentration with acylated ghrelin, growth hormone, insulin resistance, and lipid profile in o...

متن کامل

The effects of 12-wk combined aerobic/resistance training on C-reactive protein (CRP) serum and interleukin-6 (IL-6) plasma in sedentary men

Background : The purpose of this study was to examine the influence of combined training program on C-reactive protein (CRP) serum and interleukin-6 (IL-6) plasma concentrations in sedentary men. Materials and Methods: In this quasi-experimental study, twenty sedentary men (23±2 years) volunteers (with no history of regular exercise program, weight deviation more than 2 kg, special disease and...

متن کامل

Changes of Interleukin-6 and brain-derived neurotrophic factor levels following acute plyometric training among inactive men

ABSTRACT Introduction: Brain-Derived Neurotrophic Factor (BDNF) plays an important role in transmission of nerve impulses, plasticity, growth, and generally in the health of nervous system. Interleukin-6 (IL-6) is involved in immune and inflammatory responses and is produced by immune cells, fibroblasts, endothelial cells, skeletal muscles, and fat tissues. The aim of this study ...

متن کامل

The effect of different intensity circuit resistance training on inflammatory and anti-inflammatory markers in obese men

Background: Obesity is associated with chronic inflammation in obese subjects, which leads to an increase of inflammatory cytokines. This study aimed to evaluate the effect of different intensity circuit resistance training on levels of interleukin 1 beta and interleukin-10 in obese men. Methods: In a semi-experimental trial during May to August 2020, 44 obese men from Tehran city were selecte...

متن کامل

The relationship between circulating levels of IL-18 and leptin, HsCRP, blood pressure and cardiorespiratory function in obese and lean men

ABSTRACT Introduction: Interleukin-18 (IL-18) is a proinflammatory cytokine that is produced in adipose tissue and skeletal muscle. The circulating levels of IL-18 increases in obesity and some metabolic and cardiorespiratory diseases. The aim of the present study is to investigate the relationship between circulating levels of IL-18 and leptin, high-sensitivity C-reactive protei...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2013